Psychiatry · Year 3 · from Psychiatry

Case 3: The Uncooperative Patient - Biopsychosocial Formulation

Patient Demographics

  • Age: 45 years old
  • Sex: Male
  • Occupation: Unemployed (former construction worker)

Chief Complaint

"I don't need to be here. The cops brought me for no reason."

History of Present Illness

The patient was brought to the emergency department by police after being found walking in traffic on a busy highway. Bystanders called 911 when he appeared confused and was yelling at passing cars. The patient is a poor historian and is uncooperative with the interview. Limited collateral information is available. Police report states he smelled of alcohol and had an empty vodka bottle in his backpack. He is irritable and intermittently threatening, stating "I'll leave when I want to leave." When asked about walking in traffic, he states "I was just trying to get somewhere." He refuses to answer questions about suicidal ideation, stating "That's none of your business."

Mental Status Examination

Appearance: Middle-aged man appearing older than stated age, malodorous (alcohol, body odor), disheveled clothing with stains, unshaven with poor dentition, visible tremor of hands

Behavior: Hostile, uncooperative, frequently interrupts interviewer, attempts to leave the room multiple times, pacing when seated

Speech: Loud volume, rapid rate, slurred articulation, profane

Mood: "Pissed off"

Affect: Irritable, labile, dysphoric at times when discussing his situation

Thought Process: Difficult to assess due to poor cooperation; appears disorganized with frequent tangents and difficulty staying on topic

Thought Content: Limited assessment possible; denies suicidal intent when directly asked but refused to elaborate; no overt paranoid ideation expressed; preoccupied with leaving the hospital

Perceptions: Unable to assess thoroughly; no obvious response to internal stimuli observed

Cognition:

  • Alert but disoriented to date (states "I don't know, maybe Tuesday?" when it is Saturday)
  • Attention impaired - unable to complete serial 7s or spell WORLD backward
  • Memory: Unable to recall events leading to hospitalization; remote memory grossly intact

Insight: Poor - does not acknowledge any problems with substance use or behavior

Judgment: Poor - walking in traffic, refusing evaluation, threatening to leave

Psychiatric Workup

Screening Tools:

  • Unable to complete standardized assessments due to poor cooperation
  • CIWA-Ar score: 12 (moderate withdrawal risk)
  • AUDIT-C: Unable to complete

Laboratory Studies:

  • Blood alcohol level: 285 mg/dL
  • Urine drug screen: Positive for alcohol, negative otherwise
  • Glucose: 68 mg/dL (low)
  • CMP: K+ 3.2 mEq/L (low), Mg 1.4 mg/dL (low), otherwise normal
  • CBC: MCV 104 fL (elevated, suggesting chronic alcohol use)
  • Liver function: AST 78, ALT 45, GGT 124 (elevated)
  • Ammonia: 35 mcg/dL (normal)
  • CT Head: No acute intracranial abnormality

Biopsychosocial Formulation

Biological Factors:

  • Acute alcohol intoxication (BAL 285)
  • At risk for alcohol withdrawal
  • Evidence of chronic alcohol use (elevated MCV, LFTs)
  • Electrolyte abnormalities (hypokalemia, hypomagnesemia)
  • Hypoglycemia contributing to altered mental status

Psychological Factors:

  • Poor frustration tolerance
  • Limited insight into substance use
  • Possible underlying depression or trauma (requires further assessment when sober)
  • Hostility may represent defense mechanism

Social Factors:

  • Unemployment
  • Apparent homelessness (belongings in backpack)
  • Unclear social support
  • Brought by police, suggesting limited resources for self-care

Diagnosis

Provisional Diagnoses:

  1. Alcohol Use Disorder, Severe (F10.20) - pending confirmation of DSM-5 criteria when patient is sober
  2. Alcohol Intoxication (F10.129)
  3. Suicidal ideation, unspecified - cannot rule out given behavior and refusal to discuss

Treatment Plan

Acute Management:

  • Medical admission for detoxification and medical stabilization
  • CIWA-Ar protocol with lorazepam
  • IV fluids with dextrose, thiamine, folate
  • Electrolyte repletion (potassium, magnesium)
  • 1:1 observation until suicidality can be properly assessed

Re-assessment:

  • Complete psychiatric evaluation when BAL <100 and patient is not in active withdrawal
  • Collateral information (attempt to contact family, review prior records)
  • Assess for comorbid psychiatric conditions

Disposition Planning:

  • Social work consultation for housing, benefits
  • If alcohol use disorder confirmed, discuss treatment options (inpatient rehabilitation vs. intensive outpatient)
  • Assess motivation using motivational interviewing techniques

All cases for this lecture as Markdown